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Sanofi Group Sr. Principle scientist in Waltham, Massachusetts

Position Overview: Senior Principle Scientist, Lab Head, Non-viral Gene therapy, Genomics Medicine Unit

We are seeking a well-established Sr. Principle Scientist to join Sanofi Genomics Medicine Unit to lead the development of non-viral gene therapy platform technology for the treatment of liver centric, ocular and neuromuscular genetic diseases

Key Responsibilities:

  • Lead the development of non-viral gene therapy strategies and manage research for the treatment of liver centric, ocular and neuromuscular genetic diseases

  • Responsible for applying scientific expertise and judgement to initiate, design, direct and execute experiments and/or studies in support of research and/or development project goals in a time sensitive manner.

  • Act as a hands-on contributor and impactful team leader to advance GMU research and transversal programs

  • Apply state of the art scientific and gene therapy industry knowledges to develop new gene expression systems and novel gene delivery technologies

  • Foster creativity, productivity, execution with a sense of urgency, teamwork, accountability, cross-functional collaboration, and employee growth and development.

  • Work across R&D organization to identify adequate skill sets/resources to ensure progress programs in a timely manner

  • Develop and maintain a culture of teamwork and collaboration.

Basic Qualifications:

  • PhD in Molecular Biology, or a related field, plus minimum 5 years of relevant research experience in an academic or biopharmaceutical setting demonstrating continuous growth in depth and breadth of knowledge

  • Leading-edge knowledge of principles, concepts and practices in non-viral gene therapy including LNP delivery is required. AAV gene therapy and use of baculovirus system and stable producer cell line for AAV and DNA productions is a plus. Familiarity with muscle and liver targeting of therapeutics a plus.

  • Demonstrated subject matter expertise in modern molecular biology techniques, along with the ability to quickly absorb new technologies in the field, take initiative and identify new projects.

  • Strong track record of peer-reviewed publications in the field of gene therapy.

  • Hands-on manager and experienced leader of other scientists and directing research projects with a proven track record of being a results-oriented leader of cross-functional teams.

  • Ability to design, execute and generating complete research data packages to support regulatory fillings

  • Flexibility to rapidly changing priorities and deadlines and ability to lead others through change in a dynamic, fast paced industry and work environment.

  • Excellent interpersonal and communication skills: impactful oral and written communication.

  • Ability to effectively communicate, coordinate and collaborate in a multi-disciplinary team environment

  • Experience in preparing high quality documents including technical reports, presentations, SOPs, experimental protocols and regulatory filings.

  • Candidates must be authorized to work in the USA.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.



At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.