Sanofi Group Senior Research Associate, Genomic Medicine Cell Culture in Waltham, Massachusetts
The Genomic Medicine Unit (GMU) CMC group at Sanofi is dedicated to the establishment of best in class manufacturing platforms to support development of life-changing advanced cell and gene therapy products, including recombinant AAV vectors, lentiviralvectorsand cell therapy products.This organization encompasses vector and cell line engineering, upstream and downstream process development, analytics, and clinical manufacturing support.
Thecell culture processdevelopment group is responsible forviralvector production optimization and development of next generation production platforms to support high dose therapeutic products. The group is seeking a motivatedSeniorResearch Associateto join the team.
Support theexecutionand data analysis forviral vectorproductionprocess developmentexperiments.
Workwith risk group 2 infectious materials, follow safe lab procedures and maintain good laboratory practices (GLPs).
Contribute to technical reportsandprotocols.
Support maintenance of facility infrastructure and management of assay reagent,controland standard inventories, as well as other support requirements.
Collaborate with team to identify areas for improved operational excellence.
Stay updated on new, relevant technologies and published literature tosupportinnovation within the group.
Support new technology evaluations to increase product yield and process understanding.
Independently, manage personal training schedules as per established procedures.
Communicate effectively with teams.
Display sound technical judgement.
Perform weekend and holiday work to support on-going lab activities.
Master’s degreeinbiological scienceengineeringor relateddisciplineor a Bachelor’s degreewith a minimum of 2 years of relevant experience in the life sciences, biotechnology or pharmaceutical industry.
Aseptic skills as demonstrated by experiences with a variety of cell line maintenance and expansion.
Understanding of mammalian cell culture processes (thaw to production).
Knowledgeandunderstandingofcell cultureand viral vector production systems.
Understanding of key test performance indicators,monitoringand trending of data.
Ability to stand and work with lab bench equipment.
Goodorganizational, recordkeeping, and communicationskills.
Understanding of viral process development concepts.
Experience of bioreactor operations (up to several hundred L scale) and cell culture processes.
Ability to work on multiple tasks simultaneously.
Abilityto work under moderate supervision and function within a collaborative/team-orientedenvironment.
Knowledgeof Design ofExperiments(DoE’s)usingJMP orequivalentsoftwarewhileappliedtocellcultureprocesses.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.