Sanofi Group Principal Scientist - Cell Biology Screening in Waltham, Massachusetts

Principal Scientist

Description of Position:

The Cell Biology Team in the In Vitro Biology Department of Sanofi-Genzyme’s Integrated Drug Discovery Platform is seeking an experienced and highly-motivated Principal Scientist. The job entails supporting early drug discovery projects by testing small molecule candidates in various cellular models and assays. A thorough understanding of the drug discovery process is required. The successful candidate should be able to establish cellular models to support multiple therapeutic areas as well as characterize these models for target/disease relevance. As an active, enthusiastic member of project teams, the candidate will work collaboratively with medicinal chemists, biologists, pharmaceutical scientists and must be able to present scientific results at team meetings. With an appropriate sense of urgency, the successful candidate will bring valuable experiences to address scientific questions with new methods and processes.

Minimum qualifications:

The successful candidate will have a Ph.D. with 3-5 years of professional experience developing in vitro assays in the biotech/pharmaceutical environment. Experience working on early-stage drug discovery project teams is required.

Preferred qualifications:

  • The job requires extensive experience developing and validating in vitro cellular screens, backed by solid technical skills in cellular characterization and target probing techniques (CRISPER, siRNA modulation..).

  • Knowledge of high-content screening is a plus, as is familiarity with derivation, differentiation, maintenance of iPSC’s.

  • The successful candidate will become a resource across the IVB platform and must possess both management experience and demonstrate mentoring abilities in addition to excellent writing and presentation skills.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.



At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

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