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Sanofi Group Sr. RA – Delivery & formulation development in Lexington, Massachusetts

In the race for the future of health – The Sanofi mRNA Center of Excellence

At Sanofi, we believe in a world in which no one suffers or dies from vaccine-preventable diseases. And while the pandemic has shaken up our industry, creating new opportunities and risks, we believe the acceleration of innovation with mRNA technology means vaccines for more people faster than before. That’s why we’re looking for bold, optimistic world-changers to join the team at our mRNA Center of Excellence. We’re investing €400m a year into the new Center, hiring a team of 400 dedicated employees for it and using it as the foundation to implement integrated end-to-end mRNA vaccine capabilities and research with R&D, digital and CMC teams.

Company Overview

Translate Bio, a Sanofi Company is a leading mRNA therapeutics company developing a new class of potentially transformative medicines to treat diseases caused by protein or gene dysfunction. Using our proprietary mRNA therapeutic platform (MRT), we create mRNA that encodes functional proteins. Our mRNA is delivered to the target cell where the cell’s own machinery recognizes it and translates it, restoring or augmenting protein function to treat or prevent disease.

Key Responsibilities

  • Prepare formulations and perform characterization assays /data analysis with focus on in vivo studies, drug carrier design/development, assay development etc.

  • Support vaccine formulation development activities.

  • Contribute in the development & writing/reviewing analytical method protocols.

  • Prepare technical reports and presentations for clear communication of scientific findings across interdisciplinary teams.

Basic Qualifications

  • B.S./M.S. in Chemistry/Physical Chemistry/Chemical Engineering/Biochemistry

  • 0 - 6 years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle (LNP) formulations & characterization

  • Direct experience with messenger RNA encapsulation/quantification/characterization/handling is preferred

  • Proficiency in analytical techniques like HPLC/UPLC, DLS, CD, zeta potential, UV-Vis and fluorescence spectrophotometry etc. is preferred

  • Understanding and success in implementation of RNA-related analytics (Ribogreen, gel electrophoresis, capillary electrophoresis, etc.) is desired.

  • Experience in developing LNP formulations for Gene/ cell immunotherapy would be advantageous

  • Works collaboratively within group as well as within interdisciplinary teams

  • Manages time effectively demonstrating ability to perform multiple projects at one time

  • Desire to work in a fast-paced environment

  • Excellent organizational and communication skills

  • Strong analytical and problem-solving skills

As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health.This position will require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

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