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Sanofi Group Senior Associate Scientist – Renal and Musculoskeletal Diseases in Framingham, Massachusetts

Senior Associate Scientist – Renal and Musculoskeletal Diseases

We are seeking a highly motivated Senior Associate Scientist to join a team of researchers developing new therapies for rare musculoskeletal diseases. The position is based in Framingham, MA, within the Renal and Musculoskeletal Cluster of the Rare and Neurological Diseases Research Therapeutic Area at Sanofi. The candidate will execute, with moderate supervision, in vitro and in vivo pre-clinical pharmacology and mechanism-of-action studies in models of musculoskeletal disorders to support the progress of gene therapy, biologics and small molecule drug discovery programs. The Senior Associate Scientist will generate, analyze and present data of high-quality to project teams and will be expected to maintain laboratory documentation in accordance to Sanofi’s standards. Experience with modern techniques for the analysis of protein expression and function is highly desirable.

Key Responsibilities:

  • Works collaboratively as part of a research team that discovers and develops novel therapeutic agents for rare musculoskeletal disorders

  • Conducts experiments in multiple in vivo and in vitro biological systems relevant to musculoskeletal disorders

  • Follows directives in an expeditious manner to aggressively achieve goals within the expected timelines

  • Regularly presents at project team and departmental meetings

  • May contribute to the preparation of publications, intellectual property, research and clinical/regulatory documentation in accordance with the quality standards established by Sanofi

  • Commits to operational excellence according to the values and ethics expected of every employee at Sanofi

Qualifications and skills:

  • Bachelor Degree in molecular biology or related field with 3+ or Master Degree with 1+ years of experience, respectively, in an industrial or academic research laboratory

  • Hands-on experience with protein extraction from subcellular compartments (i.e. lysosome, cell membrane, nucleus), whole cells, and tissues

  • Experience with immunohistochemistry/immunofluorescence techniques for the analysis of protein expression and localization in cell cultures or tissue sections by wide field and/or confocal microscopy

  • Proficiency in recombinant DNA technologies, PCR- and qPCR, CRISPR/Cas9 gene knockout and shRNA/miRNA gene knockdown techniques.

  • Experience with aseptic techniques for the culture of primary cells and cell lines

  • Competence with use of software for statistical analysis and slide presentation

  • Familiarity with laboratory automation would be an advantage over similarly qualified candidates

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.

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