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Sanofi Group Scientist, Biologics Characterization-Mass Spectrometry in Framingham, Massachusetts


This scientist position resides within the Bioanalytics Characterization group which is a part of the Biologics Development organization. The successful candidate will utilize advanced bioanalytical tools with a focus on mass spectrometry and chromatography based techniques to characterize a variety of biotherapeutics at all stages of development to enable critical decision-making and ensure the successful development of new drugs.


  • Identify sequence liabilities in therapeutic proteins to assist pre-candidate selection in developability assessment.

  • Perform detailed structural characterization including protein sequence confirmation, sequence variant identification, qualitative and quantitative analysis of post-translational modifications (e.g. glycosylation and disulfide bonds) in support of batch release, IND enabling studies, forced degradation and comparability studies.

  • Collaborate with group members and cross functional teams to support structure-function studies, process development, and formulation studies.

  • Evaluate and develop new technologies to improve the quality and efficiency of the characterization workflows and to solve problems encountered during drug development.

  • Author technical reports, study protocols and manuscripts for publication; present at internal and external seminars and conferences.

Basic Qualifications:

  • PhD in Biochemistry or a relevant discipline, or a Master's degree with a minimum of 4 years of experience, or a Bachelor's degree and at least 6 years of experience

  • Expertise in protein mass spectrometry including LC-MS intact protein analysis, peptide mapping, and PTM characterization.

  • Highly motivated, organized, detail-oriented and able to work in a fast-paced team environment

  • Strong problem-solving and communication skills

Preferred Qualifications:

  • Experience in glycoprotein and antibody characterization

  • Experience with analytical separation methods, biophysical characterization techniques, and high throughput automation platforms

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.



At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.