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Sanofi Group Manager - Evidence Synthesis in Chilly-Mazarin, France

Job overview

  • Serve as project lead for designated therapeutic areas within Real World Evidence Generation to conduct direct (pairwise) meta-analysis / network meta-analysis / indirect treatment comparison in support of medical affairs, market access or reimbursement evidence needs.

  • Develop or review study protocols / statistical analysis plans; ensure the highest standards of excellence are applied to these studies from scientific perspective and in full compliance with Sanofi SOPs and requirements from health authorities.

  • Identify, select vendors and manage deliveries in collaboration with internal stakeholders.

  • Interpret, communicate the findings to internal audience and publish externally in scientific congress, peer-reviewed journals.


  • Consult with Medical Affairs, Health Economics, Value & Access (HEVA), and Real World Evidence Investigators to ensure timely execution to meet evidence needs.

  • Design and conduct analysis for direct (pairwise) meta-analysis, network meta-analysis (NMA) or indirect treatment comparisons (ITC), ensure compliance with best scientific practices and create study reports.

  • Provide statistical expertise to effectively communicate the findings within cross-functional teams including Medical Affairs, HEVA, Clinical Development, Biostatistics, and local affiliates.

  • Manage external vendors for the delivery of study protocol, statistical outputs and study reports.

  • Develop or review statistical inputs and results in submitted materials to external stakeholders, including scientific congress, peer-reviewed journals, regulatory/HTA submissions, core value dossiers etc.

Requirements & Qualifications

  • MSc or PhD in Statistics, Biostatistics or related quantitative sciences.

  • Minimum 5 years working experience as a statistician supporting clinical trials, RWE or HEOR studies, medical affairs or clinical development.

  • Good knowledge of Systematic Literature Review methodology (mandatory).

  • Good knowledge of NMA/ITC (mandatory).

  • Good knowledge of R, Winbugs/OpenBUGS.

  • Previous experience with submissions to regulatory and/or core value dossier development.

  • Good knowledge of technical guidelines (e.g. NICE DSU).

  • Excellent communication skills in English, both written and oral.

  • Ability to communicate effectively the methods and results of complex analyses to a wide range of audience.

  • Ability to function autonomously and manage the delivery of projects with quality control.

  • Ability to work effectively in a team environment.

  • Excellent project management skills and ability to meet deadlines.

  • Flexibility to adapt to diverse clients and project needs.

  • Demonstrated records of publication activities.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.



At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.