Sanofi Group Senior/Principal Scientist RNA Biology in Cambridge, Massachusetts
About the Role: Senior/Principal Scientist, RNA Biology based in Cambridge, MA
As an experienced RNA Scientist with proven competency in molecular and cell biology, you will be in charge Independently plan, design, and execute molecular biology, RNA biology experiments to support advancement of mRNA 2.0 vaccine platform.
In the race for the future of health – The Sanofi MRNA Center of Excellence
At Sanofi, we believe in a world in which no one suffers or dies from vaccine-preventable diseases. And while the pandemic has shaken up our industry, creating new opportunities and risks, we believe the acceleration of innovation with mRNA technology means vaccines for more people faster than before.
That’s why we’re looking for bold, optimistic world-changers to join the team at our mRNA Center of Excellence. We’re investing €400m a year into the new Center, hiring a team of 400 dedicated employees for it and using it as the foundation to implement integrated end-to-end mRNA vaccine capabilities and research with R&D, digital and CMC teams.
Bring your ambition and optimism for the future to Sanofi. Join us
In this role you will….
Able to perform advanced in vitro and ex vivo studies utilizing nucleic acid bio-analytics, and wide range of cell biology and optical microscopy analysis.
Evaluate potency of novel mRNA delivery vectors in cellular models including primary cells as well as perform plate-based assays including functional assays and multiplex detection of mRNA.
Develop, evaluate, and implement new molecular biology technology and optimize existing techniques and workflows while maintaining competitive scientific awareness, engage in scientific network.
Responsible for data analysis, data interpretation, presentation and reporting of experimental results.
Function in highly collaborative cross functional teams.
Make scientific presentation and report project progress in mRNA center of excellence team meetings.
Qualifications/ Education & work experience
PhD in molecular biology or cell biology with at least 3+ years’ experience in a research laboratory or biopharma / biotech company setting.
Very strong molecular and RNA biology background with extensive hands-on experience in cell-based and molecular biology.
Hands on experience and expertise in molecular cloning, DNA amplification technology, IVT, and purification and analytical tools of DNA, RNA and protein (gel electrophoresis, enzyme reactions immunoblotting, ELISA, Nanodrop, fragment analyzer), QPCR.
Understanding of RNA structure, cell biology, cell culture tools, florescence and confocal microscopy, quantitative image analysis, MERFISH.
Experience in developing bio-chemical assays for mechanistic understanding.
Passionate about contributing to biotechnology and mRNA vaccine technology
"Can Do and Will Do” attitude and innovative mindset.
Demonstrated ability/willingness to quickly learn and perform in new areas, implement new techniques and instrumentation.
Elaborate, structured and accurate way of working.
Ability to proactively communicate, work in multidisciplinary work stream.
Ph.D. or MSc in immunology or related field with at least 3 years of experience.
Independence in experimental design and execution, data analysis, interpretation, and presentation of in vitro / in vivo analysis of immune responses.
Proficiency with multiple cutting-edge technologies to assess immune cell function including, but not limited to, cell imaging, ELISA/ELISOPT, cytotoxicity assays, multi-parameter flow cytometry, Luminex technologies.
Ability to be self-motivated and accomplish job tasks with little supervision.
Demonstrate Play to Win Culture Behaviors.
Inspire your Journey: What Sanofi can offer you?
An international & agile work environment, in which you can develop your talent and realize.
Ideas and innovations within a competent team.
An attractive, market-oriented salary aligned with your qualifications and including social benefits above average (e.g. company pension plans, health management).
An individual and well-structured introduction and training when you onboard.
You can create your own career path within Sanofi. Your professional and personal development will be supported purposefully.
As a globally successful and constantly growing company, Sanofi provides international career paths as well.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.