Sanofi Group Senior Principal Scientist I / Lab Head – Sanofi Immuno-Oncology in Cambridge, Massachusetts

Sanofi is a global health care leader that is transforming the oncology research and development paradigm. Our goal is to create a dynamic and exciting environment that is dedicated to cutting-edge science and delivering novel life-saving therapies to cancer patients. As a part of our team, you will have an opportunity to work with talented and passionate colleagues in Sanofi Immuno-Oncology Research which is a global organization located in Cambridge, USA and Vitry-sur-Seine, France

We are seeking an experienced senior scientist to lead a group to develop next generation of IO drugs for the treatment of human malignancies. The position is based in Cambridge, Massachusetts, USA. The successful candidate will have the opportunity to develop new projects, as well as contribute to the progression of existing portfolio in Immuno-Oncology.

Job description:

  • Works as part of a research team to elucidate novel biology and discover and develop new therapeutic modalities for cancer immunotherapy

  • Works with Immuno-Oncology leaders to define new strategic initiatives, project objectives and priorities and aggressively drive execution of research to milestones

  • Contributes expertise and knowledge to the evaluation of external opportunities in Immuno-Oncology

  • Acts as primary Immuno-Oncology contact for internal and external collaborations in the field. Actively contributes to the design of collaborative projects, oversees progress and drives towards agreed-upon milestones

  • Identifies gaps in knowledge or expertise in Immuno-Oncology and makes innovative recommendations for improvements

  • Independently designs and implements laboratory experiments. Makes detailed observations, performs complex analysis of data, and details experimental design/protocol for every laboratory experiment. Assures the completeness and consistency of data from projects and experiments. Summarizes/reports the data and generates presentation materials.

  • Expected to present at lab and group meetings, global project team meetings, site meetings, and to provide materials/slides for other scientists at project or unit presentations

  • Demonstrates innovation in research/planning and expected to be able to make intellectual property submissions

  • Demonstrates the ability to manage 3-5 direct reports, including Ph.D. level scientists, in a professional manner

  • Demonstrates the ability to lead a matrixed project team of moderate-to-high complexity and to independently lead project team meetings and scientific discussions

  • Allocates resources appropriately in order to ensure overall performance within the group

Basic Qualifications:

  • Ph.D. in Immunology, Immuno-Oncology or related discipline

  • Minimum of 10+ years of research experience with a deep knowledge of basic immunological mechanisms and tumor immunology

Preferred Qualifications

  • Prior experience in Immuno-Oncology drug development is preferred

  • Solid track record of independent research accomplishments in Immuno-Oncology or related discipline, as evidenced by publications in peer-reviewed journals

  • Experience in isolation and immuno-phenotyping of murine and human immune populations using standard immune assays and immunology techniques including flow cytometry, ELISA, and Luminex

  • Expert knowledge of various murine tumor models including isolation and characterization of tumor-infiltrating lymphocytes, cytokine measurements and other relevant techniques

  • A familiarity with next generation sequencing approaches for immune phenotyping (e.g. RNAseq) and ability to collaborate with genomics/bioinformatics group in design and interpretation of studies

  • The ability to effectively communicate, collaborate and lead others

  • Must be highly collaborative and able to work effectively in a matrix environment

Sanofi US Services, Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.

Sanofi, Empowering Life

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.

Sanofi, Empowering Life