Sanofi Group Scientist in Cambridge, Massachusetts
Scientist, Type 2 Immunity and Fibrosis, Immunology and Inflammation Research
We are seeking a highly motivated and creative Scientist to join the Immunology and Inflammation Therapeutic Area located in Cambridge MA. Focusing on Type 2 inflammation and Fibrosis, your position will contribute to and direct our research towards identifying and validating novel targets, and drive discovery research programs into early clinical development. The position requires an ability to work independently, have excellent written and oral communication skills, and work effectively in a collaborative team environment.
We are seeking candidates with a strong working knowledge and demonstrated scientific success in the field of Type 2 immunity with the ability to lead scientific discoveries through cutting-edge technologies and innovation. The ideal candidate will possess strong laboratory experience and technical expertise in molecular and cellular immunology (including ELISA and cytokine multiplex assay systems, cell and tissue culture, sample preparation, acquisition and analysis using flow cytometry, primary immune cell assays and ex vivo analysis). Experience with single cell, next generation sequencing and bioinformatic analysis are strongly desired.
Summary of Key Responsibilities:
Scientific contribution and leadership towards novel target identification and validation
Scientific contribution and leadership in drug discovery project teams, working with scientific platform teams to advance projects from discovery into early clinical development.
Design, develop and perform experiments to characterize targets and pathways to select functional antibody or small molecule therapeutic candidates. Hands-on laboratory contribution is essential.
Analyze, interpret, and document data and communicate results in team, group, and leadership settings
Prepare publications, research, and clinical/regulatory documentation in accordance with Sanofi quality standards.
- PhD in immunology or a related field with 0+ years, or MS with 3+ years of relevant research experience in an academic or biopharmaceutical setting
1-3 years of postdoctoral training, industry experience.
A broad & deep understanding of the pathophysiology, molecular mechanisms, and common therapeutic paradigms in Type 2 immunity (e.g., allergy, atopy).
A broad understanding of immunological/mechanistic interdependencies and drug discovery paradigms across inflammatory and autoimmune diseases.
Strong hands-on in vitro experimental biology skills in immunology (e.g., multicolor flow cytometry, and functional assay development using human and mouse immune cells),
DNA/RNA/protein quantification platforms (e.g., Nanostring, qPCR, MSD, Luminex)
Experience in single cell and next generation sequencing assays is highly desired.
Bioinformatics analysis capability for sequencing analysis using tools or pipelining is a plus (e.g. IPA, Cell ranger, Array studio, SeqGeq, and experience with R).
Knowledge and/or experience with systems biology principles and tools (e.g., generating and/or exploring high dimensional datasets to generate and test biological hypotheses)
Excellent organization, communication, presentation, and interpersonal skills
A creative, problem-solving, collaborative, and goal-oriented mindset
Fundamental pharmacological principles in drug discovery
Sanofi, a global healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients’ needs. Sanofi has core strengths in diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal health and Genzyme.
At Sanofi US, we are committed to the growth of our people, connected in purpose by career, life and health.
Headquartered in Bridgewater, NJ, Sanofi US is part of a leading global healthcare company dedicated to discovering, developing and distributing therapeutic solutions focused on patients’ needs.
Sanofi has core strengths in diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal health and Genzyme.
Sanofi US employs approximately 17,000 people across the country all dedicated to protecting health, enhancing life and responding to the hopes and potential healthcare needs of seven billion people around the world.
Commitment is our Strength. Ready to grow together?
Sanofi US endeavors to make our career center accessible to any and all users. If you are experiencing difficulty and need assistance applying online, please call 1-800-207-8049 Option 7, then Option 3.
Sanofi US Services, Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.