Sanofi Group Scientist in Cambridge, Massachusetts
The Immunology and Inflammation Research and Early Development Therapeutic Area in Sanofi is building a world-class immunology team and is seeking highly motivated scientists to work with immunologists and associate scientists in the department to design, execute and analyze the data from in vitro and in vivo studies of immune function. The candidate will be expected to create experimental plans, implement in vitro assays, perform assays, as well as prepare reports and present results. The candidate must have strong immunology background and experience in immunological or cell signaling and molecular assays relevant to autoimmune and inflammatory diseases. The candidate is expected to be the key biologist of an ongoing project as well as to champion a new target for the drug discovery effort.
Manage laboratory inventory and keep lab record.
Isolate primary immune cells from human whole blood, design and perform phenotypic analysis by flow cytometry.
Establish in vitro immunological and cellular assays to evaluate the biological functions of target molecules in human immune cells.
Perform multiplex cytokine assay and Alphalisa cytokine assay.
Analyze complex data sets including RNA-seq and single cell RNA-seq data.
Independently design and execute experiment plans and interpret study observations.
Effectively record and report experiments.
Present results in science review meetings.
PhD with less than 4 years of relevant experience in immunology and in vivo pharmacology (including postdoctoral academic training) OR
Bachelor or Master degree with significant relevant experience in immunology and in vivo pharmacology (minimum of 8 years) and accomplishments.
Prefer 2+ year’s post-doctoral training in immunology or related field.
Working experience in analyzing complex data including those from FACS and RNA-seq data analysis is highly desirable.
Experience with in vitro functional assays using human immune cells is highly desirable.
Extensive experience in flow cytometry and cell sorting.
Excellent written and oral communication skills with track record of publication.
Knowledge in co-stimulatory and co-inhibitory pathways is highly preferred.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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